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Some RA patients don’t fit the standard profile

Identifying an autoinflammatory component in your patient’s RA is a multifactorial process. Start by reviewing a few general criteria for some important context.

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Three large circles surround a small circle that says RA MAY BE AUTOINFLAMMATORY. The larger circles have descriptions of different symptoms, treatment failures, and elevated acute phase reactants
Three large circles surround a small circle that says RA MAY BE AUTOINFLAMMATORY. The larger circles have descriptions of different symptoms, treatment failures, and elevated acute phase reactants
Next

Answer a few questions to see whether KINERET could be right for your patient.

Answer a few questions to see whether KINERET could be right for your patient.

Next

Find out if your patient is right for KINERET.

Just answer these 4 simple questions.

If you have a patient with difficult-to-treat RA, this 60-second survey may help you determine whether he or she is suitable for KINERET.

Begin

PP-5625

  • 1
    Steroid Response
  • 2
    Treatment History
  • 3
    Signs and Symptoms of Inflammation
  • 4
    Acute Phase Reactants
  • Results

Has your patient been prescribed steroids?

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Does your patient have persisting inflammatory symptoms despite steroid treatment?

Has your patient tried and failed any treatments within the following therapy classes? Check all that apply.

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How many signs and symptoms of extraarticular inflammation has your patient experienced? Check all that apply.

Has your patient exhibited any other potential indicators, such as elevated CRP or ESR levels?

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Kineret candidates typically try and fail steroids, DMARDs, and anti-TNFs before initiating therapy, although this isn’t always the case.1, 3, 5

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While Kineret may not be right for your patient at this time, it is important to understand the signs and symptoms of interleukin-1 (IL-1)—driven inflammation for future consideration1-5:

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  • Steroid resistance
  • Lack of response to DMARDs and anti-TNFs
  • Extra-articular signs and symptoms, such as fever, rash, headache, fatigue, muscle-related symptoms, keratoconjunctivitis sicca or dry eyes
  • Elevated acute phase reactants (CRP and ESR)

Your patient might be right for Kineret

Based on your answers, your patient’s RA might be mediated by interleukin-1 (IL-1), which could mean he or she is a candidate for Kineret.3

Steroid resistance, lack of response to DMARDs/anti-TNFs, extra-articular evidence of inflammation, or elevated CRP or ESR can be signs of IL-1–driven autoinflammation.1-5

To refer your patient for Kineret treatment, download our referral form.